Nomogram to predict risk of early mortality following definitive or adjuvant radiation and systemic therapy for head and neck cancer.

ABSTRACT:

Purpose/objectives

We sought to create nomograms to predict individual risk of early mortality, which can identify patients who require interventions to prevent early death.

Methods

We included patients in the National Cancer Database with non-metastatic squamous cell carcinoma of the head and neck who received radiation and systemic therapy between 2004 and 2017 in the definitive or adjuvant setting. Early mortality was defined as any death less than 90 days after starting radiation. Multivariable logistic regression was used to assess the relationship between covariates and early mortality. Nomograms to predict the risk of early death were created for both the definitive and adjuvant settings.

Results

Among 84,563 patients in the definitive group and 18,514 patients

SUBMITTER: Raab G 

PROVIDER: S-EPMC10832379 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature