Hand function after neonatal stroke: A graph model based on basal ganglia and thalami structure.

ABSTRACT:

Introduction

Neonatal arterial ischemic stroke (NAIS) is a common model to study the impact of a unilateral early brain insult on developmental brain plasticity and the appearance of long-term outcomes. Motor difficulties that may arise are typically related to poor function of the affected (contra-lesioned) hand, but surprisingly also of the ipsilesional hand. Although many longitudinal studies after NAIS have shown that predicting the occurrence of gross motor difficulties is easier, accurately predicting hand motor function (for both hands) from morphometric MRI remains complicated. The hypothesis of an association between the structural organization of the basal ganglia (BG) and thalamus with hand motor function seems intuitive given their key role in sensorimotor function. Neu

SUBMITTER: Coupeau P 

PROVIDER: S-EPMC10832504 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature