CRUX, a platform for visualising, exploring and analysing cancer genome cohort data.

ABSTRACT: To better understand how tumours develop, identify prognostic biomarkers and find new treatments, researchers have generated vast catalogues of cancer genome data. However, these datasets are complex, so interpreting their important features requires specialized computational skills and analytical tools, which presents a significant technical challenge. To address this, we developed CRUX, a platform for exploring genomic data from cancer cohorts. CRUX enables researchers to perform common analyses including cohort comparisons, biomarker discovery, survival analysis, and to create visualisations including oncoplots and lollipop charts. CRUX simplifies cancer genome analysis in several ways: (i) it has an easy-to-use graphical interface; (ii) it enables users to create custom cohorts, as wel

SUBMITTER: El-Kamand S 

PROVIDER: S-EPMC10833466 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature