"Non-Eloquent" brain regions predict neuropsychological outcome in tumor patients undergoing awake craniotomy.

ABSTRACT: Supratotal resection of primary brain tumors is being advocated especially when involving "non-eloquent" tissue. However, there is extensive neuropsychological data implicating functions critical to higher cognition in areas considered "non-eloquent" by most surgeons. The goal of the study was to determine pre-surgical brain regions that would be predictive of cognitive outcome at 4-6 months post-surgery. Cortical reconstruction and volumetric segmentation were performed with the FreeSurfer-v6.0 image analysis suite. Linear regression models were used to regress cortical volumes from both hemispheres, against the total cognitive z-score to determine the relationship between brain structure and broad cognitive functioning while controlling for age, sex, and total segmented brain volume. We

SUBMITTER: Chohan MO 

PROVIDER: S-EPMC10833519 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature