Association between occurrence of multiple white and flat elevated gastric lesions and oral proton pump inhibitor intake.

ABSTRACT:

Background/aims

Multiple white and flat elevated lesions (MWFL) that develop from the gastric corpus to the fornix may be strongly associated with oral antacid intake. Therefore, this study aimed to determine the association between the occurrence of MWFL and oral proton pump inhibitor (PPI) intake and clarify the endoscopic and clinicopathological characteristics of MWFL.

Methods

The study included 163 patients. The history of oral drug intake was collected, and serum gastrin levels and anti-Helicobacter pylori immunoglobulin G antibody titers were measured. Upper gastrointestinal endoscopy was performed. The primary study endpoint was the association between MWFL and oral PPI intake.

Results

In the univariate analyses, MWFL were observed in 35 (49.3%) of 71 patients

SUBMITTER: Hasegawa R 

PROVIDER: S-EPMC10834278 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature