The age-related obesity paradigm: results from two large prospective cohort studies.

ABSTRACT:

Background

The obesity paradigm has been a health concern globally for many years, its meaning is controversial. In this study, we assess the characteristics and causes of obesity paradigm and detail the mediation of obesity and inflammation on survival.

Methods

The original cohort included participants from the US National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018, a prospective cohort of a nationally representative sample of adult participants; the oncology validation cohort included patients from the Investigation on Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) from 2013 to 2021, a prospective cohort of Chinese patients with cancer. Survival analysis was performed using weighted (NHANES) or unweighted (INSCOC) Cox survival anal

SUBMITTER: Ge YZ 

PROVIDER: S-EPMC10834317 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature