Shape phenotype of thigh fat and muscle and risk of major adverse cardiovascular events after fragility hip fracture.

ABSTRACT:

Background

Although sarcopenia has been recognized as a predictor of mortality in elderly patients with hip fracture, the association of thigh fat and muscle with cardiovascular (CV) outcome remains unclear. We examined the impact of computed tomography (CT)-derived shape features of thigh fat and muscle on major adverse CV events (MACE) in elderly patients with hip fracture.

Methods

We conducted a retrospective analysis of consecutive patients aged ≥65 years who presented with hip fracture confirmed on pelvic bone CT scan and underwent hip fracture surgery at our institution from April 2019 to December 2021. The cross-sectional area (CSA) and compactness (CM) of both the muscle and fat at the upper-thigh level were calculated from two-dimensional CT images using AVIEW Resea

SUBMITTER: Lee SW 

PROVIDER: S-EPMC10834328 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature