Pineal anlage tumor: clinical and diagnostic features, and rationales for treatment.

ABSTRACT:

Purpose

To provide a treatment-focused review and develop basic treatment guidelines for patients diagnosed with pineal anlage tumor (PAT).

Methods

Prospectively collected data of three patients with pineal anlage tumor from Germany was combined with clinical details and treatment information from 17 published cases.

Results

Overall, 20 cases of PAT were identified (3 not previously reported German cases, 17 cases from published reports). Age at diagnosis ranged from 0.3 to 35.0 (median: 3.2 ± 7.8) years. All but three cases were diagnosed before the age of three years. For three cases, metastatic disease at initial staging was described. All patients underwent tumor surgery (gross-total resection: 9, subtotal resection/biopsy: 9, extent of resection unknown: 2). 15/2

SUBMITTER: Obrecht-Sturm D 

PROVIDER: S-EPMC10834633 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature