Prognostic significance of pan-immune-inflammation value (PIV) in nasopharyngeal carcinoma patients.

ABSTRACT:

Background

Blood-based immune-inflammation indexes have been widely used to predict survival in a variety of cancers. In this research, we seeked to evaluate a novel immune-inflammation marker, named the pan-immune-inflammation value (PIV), in patients with nasopharyngeal carcinoma (NPC) undergoing definitive radiotherapy.

Methods

A group of 377 patients with NPC was retrospectived analyzed. Clinical data and laboratory data were collected. Receiver operating characteristic (ROC) curve analysis was performed in order to determine the optimal PIV cut-off value. Survival curves were estimated by Kaplan-Meier method, and prognostic variables were identified using a Cox regression model. Additionally, we developed a nomogram and assessed its acuracy using the concordance index (

SUBMITTER: Zhang N 

PROVIDER: S-EPMC10834807 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature