Neuronal sensorimotor integration guiding salt concentration navigation in Caenorhabditis elegans.

ABSTRACT: Animals navigate their environment by manipulating their movements and adjusting their trajectory which requires a sophisticated integration of sensory data with their current motor status. Here, we utilize the nematode Caenorhabditis elegans to explore the neural mechanisms of processing the sensory and motor information for navigation. We developed a microfluidic device which allows animals to freely move their heads while receiving temporal NaCl stimuli. We found that C. elegans regulates neck bending direction in response to temporal NaCl concentration changes in a way which is consistent with a C. elegans' navigational strategy which regulates traveling direction toward preferred NaCl concentrations. Our analysis also revealed that the activity of a neck motor neu

SUBMITTER: Matsumoto A 

PROVIDER: S-EPMC10835141 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature