Epidemiology and patterns of empiric antimicrobial therapy practice in patients with community-onset sepsis using data from a Japanese nationwide medical claims database-the Japan Sepsis Alliance (JaSA) study group.

ABSTRACT:

Objectives

We aimed to describe empiric antimicrobial options for patients with community-onset sepsis using nationwide real-world data from Japan.

Methods

This retrospective cohort study used nationwide Japanese data from a medical reimbursement system database. Patients aged ≥20 years with both presumed infections and acute organ dysfunction who were admitted to hospitals from the outpatient department or emergency department between 2010 and 2017 were enrolled. We described the initial choices of antimicrobials for patients with sepsis stratified by intensive care unit (ICU) or ward.

Results

There were 1,195,741 patients with community-onset sepsis; of these, 1,068,719 and 127,022 patients were admitted to the wards and ICU, respectively. Third-generation cephalosp

SUBMITTER: Abe T 

PROVIDER: S-EPMC10835350 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature