The Impact of Prostate-Specific Antigen Screening on Prostate Cancer Incidence and Mortality in China: 13-Year Prospective Population-Based Cohort Study.

ABSTRACT:

Background

The status of prostate-specific antigen (PSA) screening is unclear in China. Evidence regarding the optimal frequency and interval of serial screening for prostate cancer (PCa) is disputable.

Objective

This study aimed to depict the status of PSA screening and to explore the optimal screening frequency for PCa in China.

Methods

A 13-year prospective cohort study was conducted using the Chinese Electronic Health Records Research in Yinzhou study's data set. A total of 420,941 male participants aged ≥45 years were included between January 2009 and June 2022. Diagnosis of PCa, cancer-specific death, and all-cause death were obtained from the electronic health records and vital statistic system. Hazard ratios (HRs) with 95% CIs were estimated using Cox regressi

SUBMITTER: Ruan X 

PROVIDER: S-EPMC10835592 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature