Association of Skin Microbiome Dynamics With Radiodermatitis in Patients With Breast Cancer.

ABSTRACT:

Importance

The interindividual differences in severity of acute radiation dermatitis are not well understood. To date, the pathomechanism and interplay of microbiome and radiodermatitis before and during treatment remain largely unknown.

Objective

To assess the association of skin microbiome baseline composition and dynamics with severity of radiodermatitis in patients undergoing adjuvant radiotherapy for breast cancer.

Design, setting, and participants

A longitudinal prospective pilot observational study was conducted between January 2017 and January 2019. Sequencing results were received in March 2021, and the data were analyzed from August 2021 to March 2023. This study was performed at an urban academic university cancer center. A total of 21 female patients with

SUBMITTER: Hulpusch C 

PROVIDER: S-EPMC10835615 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature