DendroX: multi-level multi-cluster selection in dendrograms.

ABSTRACT:

Background

Cluster heatmaps are widely used in biology and other fields to uncover clustering patterns in data matrices. Most cluster heatmap packages provide utility functions to divide the dendrograms at a certain level to obtain clusters, but it is often difficult to locate the appropriate cut in the dendrogram to obtain the clusters seen in the heatmap or computed by a statistical method. Multiple cuts are required if the clusters locate at different levels in the dendrogram.

Results

We developed DendroX, a web app that provides interactive visualization of a dendrogram where users can divide the dendrogram at any level and in any number of clusters and pass the labels of the identified clusters for functional analysis. Helper functions are provided to extract linkage ma

SUBMITTER: Feng F 

PROVIDER: S-EPMC10835886 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature