Cytokine profile in first-episode drug-naive major depressive disorder patients with or without anxiety.

ABSTRACT:

Objective

It is known that cytokines play a role in both depression and anxiety. This study aimed to compare the levels of multiple cytokines in patients with first-episode drug-naive major depressive disorder (MDD) with or without anxiety and analyze the correlation between the level of depression or anxiety and the serum cytokine levels.

Methods

The study involved 55 patients with first-episode drug-naive MDD. To assess anxiety symptoms, the 14-item HAMA was used. MDD patients were divided into two groups: 23 MDD patients without anxiety and 32 MDD patients with anxiety. The measurement of 37 cytokines was conducted. Serum cytokine levels between patients with MDD without anxiety and anxiety were compared. In multiple linear regression models, the relationship between the

SUBMITTER: Liang J 

PROVIDER: S-EPMC10835958 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature