Characterizing diabetic cardiomyopathy: baseline results from the ARISE-HF trial.

ABSTRACT:

Background

Diabetic cardiomyopathy (DbCM) is a form of Stage B heart failure (HF) at high risk for progression to overt disease. Using baseline characteristics of study participants from the Aldose Reductase Inhibition for Stabilization of Exercise Capacity in Heart Failure (ARISE-HF) Trial we sought to characterize clinical characteristics of individuals with findings consistent with DbCM.

Methods

Among study participants meeting inclusion criteria, clinical characteristics, laboratory testing, imaging, Kansas City Cardiomyopathy Questionnaire (KCCQ), Physical Activity Scale of the Elderly (PASE) and cardiopulmonary exercise testing (CPET) results were tabulated. Cluster phenogroups were identified.

Results

Among 691 study participants (mean age 67.4 years; 50% were

SUBMITTER: Januzzi JL 

PROVIDER: S-EPMC10835978 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature