Increased vascular inflammation on PET/CT in psoriatic arthritis patients in comparison with controls.

ABSTRACT:

Background

Patients with psoriatic arthritis (PsA) have an increased risk of cardiovascular disease, possibly due to a chronic inflammatory state.

Objectives

The main objective of this study was to investigate the difference in vascular inflammation, measured with 18-fluorodeoxyglucose positron emission tomography/CT (PET/CT), in PsA patients and controls. We conducted a secondary analysis to assess the association between clinical parameters of disease activity with vascular inflammation in PsA.

Methods

We included a total of 75 PsA patients with active peripheral arthritis (defined as ≥2 tender and swollen joints) from an ongoing clinical trial (EudraCT 2017-003900-28) and a retrospective group of 40 controls diagnosed with melanoma, without distant metastases and n

SUBMITTER: Kleinrensink NJ 

PROVIDER: S-EPMC10836343 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature