Association between knee magnetic resonance imaging markers and knee symptoms over 6-9 years in young adults.

ABSTRACT:

Objectives

To describe associations between MRI markers with knee symptoms in young adults.

Methods

Knee symptoms were assessed using the WOMAC scale during the Childhood Determinants of Adult Health Knee Cartilage study (CDAH-knee; 2008-2010) and at the 6- to 9-year follow-up (CDAH-3; 2014-2019). Knee MRI scans obtained at baseline were assessed for morphological markers (cartilage volume, cartilage thickness, subchondral bone area) and structural abnormalities [cartilage defects and bone marrow lesions (BMLs)]. Univariable and multivariable (age, sex, BMI adjusted) zero-inflated Poisson (ZIP) regression models were used for analysis.

Results

The participants' mean age in CDAH-knee and CDAH-3 were 34.95 (s.d. 2.72) and 43.27 (s.d. 3.28) years, with 49% and 48% female

SUBMITTER: Singh A 

PROVIDER: S-EPMC10836990 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature