Seroepidemiology of Human Tularemia-Systematic Review and Meta-analysis of Seroprevalence Studies.

ABSTRACT:

Background

Seroepidemiologic studies of human tularemia have been conducted throughout the northern hemisphere. The purposes of this study were (1) to provide an overview of Francisella tularensis seroprevalence data, and (2) to generate an estimate of the proportion of study participants whose infection remained subclinical.

Methods

We conducted a systematic review of F tularensis seroprevalence studies according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. We searched PubMed, Embase, and Web of Science covering the period from 1951 to 2023.

Results

The weighted pooled seroprevalence among 44 486 participants recruited in 52 studies was 3.7% (95% confidence interval [CI], 2.7-5.1). Reported seroprevalenc

SUBMITTER: Mattatia C 

PROVIDER: S-EPMC10837002 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature