Silk fibroin-based inks for in situ 3D printing using a double crosslinking process.

ABSTRACT: The shortage of tissues and organs for transplantation is an urgent clinical concern. In situ 3D printing is an advanced 3D printing technique aimed at printing the new tissue or organ directly in the patient. The ink for this process is central to the outcomes, and must meet specific requirements such as rapid gelation, shape integrity, stability over time, and adhesion to surrounding healthy tissues. Among natural materials, silk fibroin exhibits fascinating properties that have made it widely studied in tissue engineering and regenerative medicine. However, further improvements in silk fibroin inks are needed to match the requirements for in situ 3D printing. In the present study, silk fibroin-based inks were developed for in situ applications by exploiting covalent

SUBMITTER: Agostinacchio F 

PROVIDER: S-EPMC10837071 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature