Oxytocin is not associated with postpartum hemorrhage in labor augmentation in a retrospective cohort study in the United States.

ABSTRACT:

Background

Previous studies reported conflicting results on the relationship between oxytocin use for labor augmentation and the risk of postpartum hemorrhage, probably because it is rather challenging to disentangle oxytocin use from labor dystocia.

Objective

This study aimed to investigate the independent association between oxytocin use for augmentation and the risk of postpartum hemorrhage by using advanced statistical modeling to control for labor patterns and other covariates.

Study design

We used data from 20,899 term, cephalic, singleton pregnancies of patients with spontaneous onset of labor and no previous cesarean delivery from Intermountain Healthcare in Utah in the Consortium on Safe Labor. Presence of postpartum hemorrhage was identified on the basis of

SUBMITTER: Zhu H 

PROVIDER: S-EPMC10837333 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature