Malaria seroepidemiology in very low transmission settings in the Peruvian Amazon.

ABSTRACT: Despite progress towards malaria reduction in Peru, measuring exposure in low transmission areas is crucial for achieving elimination. This study focuses on two very low transmission areas in Loreto (Peruvian Amazon) and aims to determine the relationship between malaria exposure and proximity to health facilities. Individual data was collected from 38 villages in Indiana and Belen, including geo-referenced households and blood samples for microscopy, PCR and serological analysis. A segmented linear regression model identified significant changes in seropositivity trends among different age groups. Local Getis-Ord Gi* statistic revealed clusters of households with high (hotspots) or low (coldspots) seropositivity rates. Findings from 4000 individuals showed a seropositivity level of 2.5% (

SUBMITTER: Fernandez-Camacho B 

PROVIDER: S-EPMC10837415 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature