Identification of a novel macrophage-related prognostic signature in colorectal cancer.
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ABSTRACT:
SUBMITTER: Lin D
PROVIDER: S-EPMC10837438 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
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Identification of a novel macrophage-related prognostic signature in colorectal cancer.
Lin Dongfa D Zheng Tingjin T Huang Shangyuan S Liu Rui R Guan Shuwen S Zhang Zhishan Z
Scientific reports 20240202 1
Colorectal cancer (CRC) is one of the most prevalent and deadliest illnesses all around the world. Growing proofs demonstrate that tumor-associated macrophages (TAMs) are of critical importance in CRC pathogenesis, but their mechanisms remain yet unknown. The current research was designed to recognize underlying biomarkers associated with TAMs in CRC. We screened macrophage-related gene modules through WGCNA, selected hub genes utilizing the LASSO algorithm and COX regression, and established a ...[more]
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