Metronomic chemotherapy and drug repurposing: A paradigm shift in oncology.

ABSTRACT: Cancer represents a significant global health and economic burden due to its high mortality rates. While effective in some instances, traditional chemotherapy often falls short of entirely eradicating various types of cancer. It can cause severe side effects due to harm to healthy cells. Two therapeutic approaches have risen to the forefront to address these limitations: metronomic chemotherapy (MCT) and drug repurposing. Metronomic chemotherapy is an innovative approach that breaks from traditional models. It involves the administration of chemotherapeutic regimens at lower doses, without long drug-free intervals that have previously been a hallmark of such treatments. This method offers a significant reduction in side effects and improved disease management. Simultaneously, drug repurpos

SUBMITTER: Jan N 

PROVIDER: S-EPMC10837507 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature