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Risk factors and an early predictive model for Kawasaki disease shock syndrome in Chinese children.


ABSTRACT:

Background

Kawasaki disease shock syndrome (KDSS), though rare, has increased risk for cardiovascular complications. Early diagnosis is crucial to improve the prognosis of KDSS patients. Our study aimed to identify risk factors and construct a predictive model for KDSS.

Methods

This case-control study was conducted from June, 2015 to July, 2023 in two children's hospitals in China. Children initially diagnosed with KDSS and children with Kawasaki disease (KD) without shock were matched at a ratio of 1:4 by using the propensity score method. Laboratory results obtained prior to shock syndrome and treatment with intravenous immunoglobulin were recorded to predict the onset of KDSS. Univariable logistic regression and forward stepwise logistic regression were used to select sig

SUBMITTER: Zhang M 

PROVIDER: S-EPMC10837898 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature