Transcriptomic and proteomic strategies to reveal the mechanism of Gymnocypris przewalskii scale development.

ABSTRACT:

Background

Fish scales are typical products of biomineralization and play an important role in the adaptation of fish to their environment. The Gymnocypris przewalskii scales are highly specialized, with scales embedded in only specific parts of the dermis, such as the areas around the anal fin and branchiostegite, making G. przewalskii an ideal material for biomineralization research. In this study, we aimed to unveil genes and pathways controlling scale formation through an integrated analysis of both transcriptome and proteome, of which G. przewalskii tissues of the dorsal skin (no scales) and the rump side skin (with scales) were sequenced. The sequencing results were further combined with cellular experiments to clarify the relationship between genes and signaling pathways.

SUBMITTER: Xu B 

PROVIDER: S-EPMC10837935 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature