The impact of platelet-to-lymphocyte ratio on clinical outcomes in heart failure: a systematic review and meta-analysis.

ABSTRACT:

Background

Inflammation has been suggested to play a role in heart failure (HF) pathogenesis. However, the role of platelet-to-lymphocyte ratio (PLR), as a novel biomarker, to assess HF prognosis needs to be investigated. We sought to evaluate the impact of PLR on HF clinical outcomes.

Methods

English-published records in PubMed/Medline, Scopus, and Web-of-science databases were screened until December 2023. Relevant articles evaluated PLR with clinical outcomes (including mortality, rehospitalization, HF worsening, and HF detection) were recruited, with PLR difference analysis based on death/survival status in total and HF with reduced ejection fraction (HFrEF) patients.

Results

In total, 21 articles (n = 13,924) were selected. The total mean age was 70.36 ± 1

SUBMITTER: Vakhshoori M 

PROVIDER: S-EPMC10838041 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature