A Physical Model-Based Approach to One-Point Calibration of Pulse Transit Time to Blood Pressure.

ABSTRACT:

Objective

To develop a novel physical model-based approach to enable 1-point calibration of pulse transit time (PTT) to blood pressure (BP).

Methods

The proposed PTT-BP calibration model is derived by combining the Bramwell-Hill equation and a phenomenological model of the arterial compliance (AC) curve. By imposing a physiologically plausible constraint on the skewness of AC at positive and negative transmural pressures, the number of tunable parameters in the PTT-BP calibration model reduces to 1. Hence, as opposed to most existing PTT-BP calibration models requiring multiple (≥2) PTT-BP measurements to personalize, the PTT-BP calibration model can be personalized to an individual subject using a single PTT-BP measurement pair. Equipped with the physically relevant PTT-AC

SUBMITTER: Mousavi A 

PROVIDER: S-EPMC10838522 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature