Successful adult domino living donor liver transplantation in methylmalonic acidemia: case report.

ABSTRACT:

Background

Liver transplantation (LT) is a therapeutic option in multiple inherited metabolic diseases (IMDs), including methylmalonic acidemia (MMA), as LT reduces the risk of acute metabolic decompensations and long-term complications associated with these diseases. In certain IMDs, such as maple syrup urine disease (MSUD), domino liver transplant (DLT) is an accepted and safe method which expands the donor pool. However, only one adult case of DLT using an MMA donor liver has been reported; outcome and safety are still unknown and questioned.

Case description

In this case report, we describe our experience with DLT using MMA livers. Two adult MMA patients underwent living donor liver transplant (LDLT); their MMA livers were consecutively transplanted into two patients on

SUBMITTER: Chorley AJ 

PROVIDER: S-EPMC10838613 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature