Regulation of regulatory T cells and tumor-associated macrophages in gastric cancer tumor microenvironment.

ABSTRACT:

Introduction

Despite advancements in the methods for prevention and early diagnosis of gastric cancer (GC), GC continues to be the fifth in incidence among major cancers and the third most common cause of cancer-related death. The therapeutic effects of surgery and drug treatment are still unsatisfied and show notable differences according to the tumor microenvironment (TME) of GC.

Methods

Through screening Pubmed, Embase, and Web of Science, we identified and summarized the content of recent studies that focus on the investigation of Helicobacter pylori (Hp) infection, regulatory T cells (Tregs), and tumor-associated macrophages (TAMs) in the TME of GC. Furthermore, we searched and outlined the clinical research progress of various targeted drugs in GC treatment including C

SUBMITTER: Shaopeng Z 

PROVIDER: S-EPMC10839124 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature