Narrative review: precision medicine applications in neuroblastoma-current status and future prospects.

ABSTRACT:

Background and objective

Neuroblastoma (NB) is a common malignant tumor in children, and its treatment remains challenging. Precision medicine, as an individualized treatment strategy, aims to improve efficacy and reduce toxicity by combining unique patient- and tumor-related factors, bringing new hope for NB treatment. In this article, we review the evidence related to precision medicine in NB, with a focus on potential clinically actionable targets and a series of targeted drugs associated with NB.

Methods

We conducted an extensive search in PubMed, EMBASE, and Web of Science using key terms and database-specific strategies, filtered for time and language, to ensure a comprehensive collection of literature related to precision medicine in NB. The main search terms consiste

SUBMITTER: Zhou J 

PROVIDER: S-EPMC10839273 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature