Efficacy and safety of a smartphone application-based treatment of ketogenic diet in pediatric refractory epilepsy.

ABSTRACT:

Objective

We aimed to find predictors for smartphone application-based ketogenic diet (KD) treatment effectiveness and safety.

Methods

The efficacy was evaluated according to the reduction in seizure frequency after the intervention of KD; safety was evaluated based on adverse effects. The ordinal logistic regression analysis was used to explore the influencing factors of efficacy.

Results

The study sample included 116 males and 65 females with a median age of 2.27 years. The baseline frequency of seizure was more than five times/day in 123 children, 50.83% of them received three or more antiepileptic drugs (AEDs). Seventy-two patients' KD initiation mode was outpatient, and 73 completed the 12-month follow-up. A total of 88 (48.62%) patients had reported a reduction

SUBMITTER: Li W 

PROVIDER: S-EPMC10839295 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature