E = mc² : Education (E), medication (m), and conditional cash (c² ) to improve uptake of antiseizure medications in a low-resource population: Protocol for randomized trial.

ABSTRACT:

Objective

Most people with epilepsy (PWE) could live seizure-free if treated with one or more antiseizure medications (ASMs). The World Health Organization (WHO) estimates that 75% of PWE in low-resource settings lack adequate antiseizure treatment. Limited education surrounding epilepsy and the out-of-pocket costs of ASMs in particular pose barriers to managing epilepsy in resource-poor, low-income settings. The aim of this study is to implement and test a novel strategy to improve outcomes across the epilepsy care cascade marked by (1) retention in epilepsy care, (2) adherence to ASMs, and (3) seizure reduction, with the measured goal of seizure freedom.

Methods

A randomized, double-blinded clinical trial will be performed, centered at the Ignace Deen Hospital in Conakry,

SUBMITTER: Rezaei SJ 

PROVIDER: S-EPMC10839367 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature