Pan-analysis reveals CACYBP to be a novel prognostic and predictive marker for multiple cancers.

ABSTRACT:

Objectives

Cancer has emerged as a global issue in terms of public health care and treatment. The significance of calcyclin binding protein (CACYBP) in various neoplasms suggests that it may serve as a novel biomarker for numerous types of human tumors.

Methods

Our research investigated the differences in CACYBP expression between cancer tissues and normal tissues using a total of 18,787 samples from multiple centers. To explore the prognostic factor of CACYBP in cancers, we utilized Cox regression analysis and Kaplan-Meier curves. We also conducted Spearman's rank correlation analyses to determine the associations of CACYBP expression with the immune microenvironment, etc. Additionally, we applied gene set enrichment analysis to explore the under

SUBMITTER: Mo B 

PROVIDER: S-EPMC10839390 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature