Unraveling the role of serum metabolites in the relationship between plant-based diets and bone health in community-dwelling older adults.

ABSTRACT: The potential adverse effects of the plant-based dietary pattern on bone health have received widespread attention. However, the biological mechanisms underlying the adverse effects of plant-based diets on bone health remain incompletely understood. The objective of this study was to identify potential biomarkers between plant-based diets and bone loss utilizing metabolomic techniques in the Taizhou Imaging Study (TIS) (N = 788). Plant-based diet indexes (overall plant-based diet index (PDI), healthy plant-based diet index (hPDI), and unhealthy plant-based diet index (uPDI)) were calculated using the food frequency questionnaire, and bone mineral density (BMD) was measured using dual-energy X-ray absorptiometry. A multinomial logistic regression was used to explore the associations of plan

SUBMITTER: Zheng Y 

PROVIDER: S-EPMC10839558 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature