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Prognostic scores in pulmonary large cell neuroendocrine carcinoma: A retrospective cohort study.


ABSTRACT:

Introduction

Pulmonary large cell neuroendocrine carcinoma (PLCNEC) is a rare but aggressive subtype of lung cancer with an incidence of approximately 3 %. Identifying effective prognostic indicators is crucial for guiding treatments. This study examined the relationship between inflammatory markers and PLCNEC patient overall survival (OS) and sought to determine their prognostic significance in PLCNEC.

Methods

Patients diagnosed with PLCNEC between 2007 and 2022 at the oncology center, were retrospectively included. Patients who underwent surgery were pathologically re-staged post-surgery. Potential prognostic parameters (neutrophil/lymphocyte ratio, platelet/lymphocyte ratio [PLR], panimmune inflammatory value, prognostic nutritional index and modified Glasgow prognostic s

SUBMITTER: Akdag G 

PROVIDER: S-EPMC10839983 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature