Micronutrients intake and genetic variants associated with premature ovarian insufficiency; MASHAD cohort study.

ABSTRACT:

Background and aim

premature ovarian insufficiency (POI) is defined as the menopause before 40 years of age, and its prevalence is reported to be two-fold higher in Iranian women than the average for woman globally. POI is associated with several cardio/cerebrovascular complications as well as an increased overall mortality. Genetic factors, and serum levels of minerals and vitamin D, have been reported to be related to the prevalence of POI. We have investigated the association between some POI -related genotypes with the serum levels of some important micronutrients.

Methods

One hundred and seventeen women with POI and 183 controls without any renal, hepatic, and thyroid abnormalities were recruited as part of the MASHAD study. Demographic and anthropometric features were

SUBMITTER: Mirinezhad MR 

PROVIDER: S-EPMC10840145 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature