Whole-Genome Sequencing of an Escherichia coli ST69 Strain Harboring bla_CTX-M-27 on a Hybrid Plasmid.

ABSTRACT:

Objective

Escherichia coli is a common Gram-negative human pathogen. The emergence of E. coli with multiple-antibiotic-resistant phenotypes has become a serious health concern. This study reports the whole-genome sequences of third-generation cephalosporin-resistant (3GC-R) and multidrug-resistant (MDR) E. coli EC6868 and explores the acquired antibiotic-resistance genes (ARGs) as well as their genetic contexts.

Methods

E. coli EC6868 was isolated from a vaginal secretion sample of a pregnant patient in China. The antimicrobial susceptibility was assessed, and whole-genome sequencing was conducted. The acquired ARGs, insertion sequence (IS) elements, and integrons within the genome of E. coli EC6868 were identified, and the genetic contexts

SUBMITTER: Wang L 

PROVIDER: S-EPMC10840416 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature