Examination of proinflammatory activity as a moderator of the relation between momentary interpersonal stress and suicidal ideation.

ABSTRACT:

Introduction

Peer-related interpersonal stress can increase risk for suicidal thoughts among adolescents and young adults. However, not all individuals who undergo peer-related interpersonal stressors experience suicidal thoughts. Heightened proinflammatory activity is one factor that may amplify the relation between interpersonal stress and suicidal thinking.

Methods

This pilot study examined the relation between interpersonal stress and suicidal ideation in real time, as well as whether proinflammatory cytokine (IL-6 and TNF-α) activity across a laboratory social stressor moderated this association in a sample of 42 emerging adults with recent suicidal ideation. Participants completed 28 days of 6×/daily ecological momentary assessment that assessed for suicidal ideation (

SUBMITTER: Defayette AB 

PROVIDER: S-EPMC10840613 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature