Perinatal Outcomes Associated With Management of Stage 1 Hypertension.

ABSTRACT:

Objective

To evaluate the association between maternal blood pressure (BP) below 130/80 mm Hg compared with 130-139/80-89 mm Hg and pregnancy outcomes.

Methods

We conducted a planned secondary analysis of CHAP (Chronic Hypertension and Pregnancy), an open label, multicenter, randomized controlled trial. Participants with mean BP below 140/90 mm Hg were grouped as below 130/80 mm Hg compared with 130-139/80-89 mm Hg by averaging postrandomization clinic BP throughout pregnancy. The primary composite outcome was preeclampsia with severe features, indicated preterm birth before 35 weeks of gestation, placental abruption, or fetal or neonatal death. The secondary outcome was small for gestational age (SGA).

Results

Of 2,408 patients in CHAP, 2,096 met study criteria; 1,32

SUBMITTER: Bailey EJ 

PROVIDER: S-EPMC10840706 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature