Sleep duration and brain MRI measures: Results from the SOL-INCA MRI study.

ABSTRACT:

Introduction

Sleep duration has been associated with dementia and stroke. Few studies have evaluated sleep pattern-related outcomes of brain disease in diverse Hispanics/Latinos.

Methods

The SOL-INCA (Study of Latinos-Investigation of Neurocognitive Aging) magnetic resonance imaging (MRI) study recruited diverse Hispanics/Latinos (35-85 years) who underwent neuroimaging. The main exposure was self-reported sleep duration. Our main outcomes were total and regional brain volumes.

Results

The final analytic sample included n = 2334 participants. Increased sleep was associated with smaller brain volume (β_{total_brain}  = -0.05, p < 0.01) and consistently so in the 50+ subpopulation even after adjusting for mild cognitive impairment status. Sleeping >9 hours was a

SUBMITTER: Gonzalez KA 

PROVIDER: S-EPMC10840814 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature