Microbiome function and neurodevelopment in Black infants: vitamin B₁₂ emerges as a key factor.

ABSTRACT: The early life gut microbiome affects the developing brain, and therefore may serve as a target to support neurodevelopment of children living in stressful and under-resourced environments, such as Black youth living on the South Side of Chicago, for whom we observe racial disparities in health. Microbiome compositions/functions key to multiple neurodevelopmental facets have not been studied in Black children, a vulnerable population due to racial disparities in health; thus, a subsample of Black infants living in urban, low-income neighborhoods whose mothers participated in a prenatal nutrition study were recruited for testing associations between composition and function of the gut microbiome (16S rRNA gene sequencing, shotgun metagenomics, and targeted metabolomics of fecal samples) and

SUBMITTER: Oliphant K 

PROVIDER: S-EPMC10841033 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature