Trends in use of antipsychotics and psychoactive drugs in older patients after major surgery.

ABSTRACT:

Background

Professional society guidelines recommend limiting the use of antipsychotics in older patients with postoperative delirium. How these recommendations affected the use of antipsychotics and other psychoactive drugs in the postoperative period has not been studied.

Methods

This retrospective cohort study included patients 65 years or older without psychiatric diagnoses who underwent major surgery in community hospitals (CHs) and academic medical centers (AMCs) in the United States. The outcome was the rate of hospital days exposed to antipsychotics, antidepressants, antiepileptics, benzodiazepines, hypnotics, and selective alpha-2 receptor agonist dexmedetomidine in the postoperative period by hospital type.

Results

The study included 4,098,431 surgical admis

SUBMITTER: Kim DH 

PROVIDER: S-EPMC10841351 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature