Longitudinal associations of physical activity with inflammatory markers in US adults with and without type 1 diabetes.

ABSTRACT:

Aims

To investigate the longitudinal associations of different levels of moderate-to-vigorous physical activity (MVPA) with C-reactive protein (CRP), plasminogen activator inhibitor-1 (PAI-1), and fibrinogen.

Methods

We conducted longitudinal analyses with data from the Coronary Artery Calcification in T1D (CACTI) cohort, which included individuals with type 1 diabetes (T1D, n = 563) and without diabetes mellitus (non-DM, n = 692) with ∼ 3 years follow-up. Individuals were divided into groups to perform two analyses: 1) those who performed any MVPA and those who were sedentary (0 mins/week) and 2) those who performed 1-149 mins/week, ≥150 mins/week, or who were sedentary. Mixed effect models with an unstructured covariance structure were applied.

Results

Compared to s

SUBMITTER: Richardson LA 

PROVIDER: S-EPMC10841646 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature