Levothyroxine for a high-normal TSH in unexplained infertility.

ABSTRACT:

Objective

Unexplained infertility affects nearly one-third of infertile couples. Women with unexplained infertility are more likely to have a high-normal thyroid-stimulating hormone level (TSH: 2.5-5 mIU/L) compared to women with severe male factor infertility. Practice guidelines vary on whether treatment should be initiated for TSH levels >2.5 mIU/L in women attempting conception because the effects of treating a high-normal TSH level with levothyroxine are not known. We evaluated conception and live birth rates in women with unexplained infertility and high-normal TSH levels.

Design, patients and measurements

Retrospective study including 96 women evaluated for unexplained infertility at a large academic medical centre between 1 January 2000 and 30 June 2017 with high-nor

SUBMITTER: Galbiati F 

PROVIDER: S-EPMC10841672 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature