White matter predictors of PTSD: Testing different machine learning models in a sample of Black American women.

ABSTRACT:

Background

Machine learning neuroimaging studies of posttraumatic stress disorder (PTSD) show promise for identifying neurobiological signatures of PTSD. However, studies to date, have largely evaluated a single machine learning approach, and few studies have examined white matter microstructure as a predictor of PTSD. Further, individuals from minoritized racial groups, specifically, Black individuals, who experience disproportionate trauma frequency, and have relatively higher rates of PTSD, have been underrepresented in these studies. We used four different machine learning models to test white matter microstructure classifiers of PTSD in a sample of trauma-exposed Black American women with and without PTSD.

Method

Participants included 45 Black women with PTSD and 89 tra

SUBMITTER: Haller OC 

PROVIDER: S-EPMC10841705 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature