The effects of medical comorbidity, cognition, and age on patient-reported outcomes in Parkinson's disease.

ABSTRACT:

Objective

The purpose of this cross-sectional study was to compare the independent contributions of medical comorbidity, cognition, and age on patient-reported outcomes in Parkinson's disease (PD).

Methods

572 PD patients completed the Patient-Reported Outcome Measurement Information System (PROMIS®)-29 v2.0 Profile (physical function, anxiety, depression, fatigue, sleep disturbance, satisfaction with participation in social roles, pain interference) and PROMIS Global Health (mental health and physical health) scales. Comorbidity was measured with the Cumulative Illness Rating Scale-Geriatric (CIRS-G) and cognition with the Montreal Cognitive Assessment (MoCA). Multiple regression models examined the 9 PROMIS measures as predicted by comorbidity, cognition, and age, adjustin

SUBMITTER: Kim H 

PROVIDER: S-EPMC10841750 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature