Emerging roles of microRNAs as diagnostics and potential therapeutic interest in type 2 diabetes mellitus.

ABSTRACT:

Background

Type 2 diabetes mellitus (T2DM) is a metabolic disease of impaired glucose utilization. Uncontrolled high sugar levels lead to advanced glycation end products (AGEs), which affects several metabolic pathways by its receptor of advanced glycation end products (RAGE) and causes diabetic complication. MiRNAs are small RNA molecules which regulate genes linked to diabetes and affect AGEs pathogenesis, and target tissues, influencing health and disease processes.

Aim

To explore miRNA roles in T2DM's metabolic pathways for potential therapeutic and diagnostic advancements in diabetes complications.

Methods

We systematically searched the electronic database PubMed using keywords. We included free, full-length research articles that evaluate the role of miRNAs in T

SUBMITTER: Shrivastav D 

PROVIDER: S-EPMC10841963 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature