Review of pediatric combined heart-liver transplantation: A roadmap to success.

ABSTRACT:

Background

Combined heart-liver transplantation (CHLT) is a promising technique to address end stage organ failure in patients with concomitant heart failure and chronic liver disease. While most experience with CHLT has involved adult patients, the expanding population of children born with univentricular congenital heart disease who underwent the Fontan procedure and develop Fontan-associated liver disease (FALD) has emerged as a growing indication for pediatric CHLT.

Methods

Currently, CHLT is performed at a select subset of experienced transplant centers, especially in the pediatric population.

Results

While technically demanding, CHLT may offer survival benefit when compared to heart transplant alone with decreased rejection of both synchronous allografts and equ

SUBMITTER: Lee JTC 

PROVIDER: S-EPMC10842164 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature