Resting state functional connectivity changes following mindfulness-based stress reduction predict improvements in disease control for patients with asthma.

ABSTRACT:

Background

The staggering morbidity associated with chronic inflammatory diseases can be reduced by psychological interventions, including Mindfulness-Based Stress Reduction (MBSR). Proposed mechanisms for MBSR's beneficial effects include changes in salience network function. Salience network perturbations are also associated with chronic inflammation, including airway inflammation in asthma, a chronic inflammatory disease affecting approximately 10% of the population. However, no studies have examined whether MBSR-related improvements in disease control are related to changes in salience network function.

Methods

Adults with asthma were randomized to 8 weeks of MBSR or a waitlist control group. Resting state functional connectivity was measured using fMRI before randomizat

SUBMITTER: Laubacher C 

PROVIDER: S-EPMC10842225 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature